SCHEMBL433574

SCHEMBL433574

Fc1[c]ccc(F)c1-c1ccc(Cl)cc1F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.35
EGLN2 Q96KS0 1/20 0.34
PTGS2 P35354 1/20 0.33
GRM2 Q14416 2/20 0.32
HSD11B1 P28845 1/20 0.32
S100A4 P26447 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
PDE4A P27815 2/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435121 0.88 AHR (0.39) HSD11B1
SCHEMBL435281 0.88 KMO (0.34) KMOEGLN2PTGS2GRM2HSD11B1
SCHEMBL433543 0.86 PTGS2 (0.36) KMOEGLN2PTGS2GRM2HSD11B1
SCHEMBL17514628 0.83 PTGS2 (0.34) KMOEGLN2PTGS2GRM2HSD11B1
SCHEMBL17514857 0.83 PTGS2 (0.37) KMOEGLN2PTGS2GRM2HSD11B1
SCHEMBL432706 0.81 IDO1 (0.35) KMOPTGS2
SCHEMBL17514854 0.79 GRM2 (0.38) KMOEGLN2GRM2HSD11B1S100A4
SCHEMBL17514822 0.79 KMO (0.35) KMOEGLN2GRM2HSD11B1S100A4
SCHEMBL17514551 0.77 NISCH (0.37) GRM2HSD11B1HTR2AHTR2CHTR2B
SCHEMBL17514805 0.77 GRM2 (0.35) KMOEGLN2PTGS2GRM2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116634876-A Mixtures and compositions comprising Fusarium A, fusarium B and fungicides 巴斯夫欧洲公司 2023-08-22 CN claimed
CN-116209355-A Composition containing haloxyfop-methyl 巴斯夫农业公司 2023-06-02 CN claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 CN claimed
CN-105050406-A Composition comprising triazole compound BASF SE 2015-11-11 CN claimed
CN-104936450-A Compositions comprising triazole compound BASF SE 2015-09-23 CN claimed
CN-104768377-A Pesticidal active mixtures comprising anthranilamides BASF SE 2015-07-08 CN claimed
CN-111201227-B Imidazolium compounds for combating animal pests 巴斯夫欧洲公司 2024-03-15 CN disclosed
CN-111683938-B Use of N-functionalized alkoxypyrazole compounds as nitrification inhibitors 巴斯夫欧洲公司 2024-01-23 CN disclosed
CN-117355519-A Novel substituted pyridines as fungicides 巴斯夫欧洲公司 2024-01-05 CN disclosed
CN-117355518-A Novel substituted pyridines as fungicides 巴斯夫欧洲公司 2024-01-05 CN disclosed
CN-117355520-A Novel substituted quinolines as fungicides 巴斯夫欧洲公司 2024-01-05 CN disclosed
CN-111491925-B Pesticidal compounds 巴斯夫欧洲公司 2023-12-29 CN disclosed
CN-117295399-A Novel microparticles containing active substances 巴斯夫欧洲公司 2023-12-26 CN disclosed
CN-104768379-A Method of controlling ryanodine-modulator insecticide resistant insects BASF SE 2015-07-08 CN disclosed
CN-104768377-A Pesticidal active mixtures comprising anthranilamides BASF SE 2015-07-08 CN disclosed
CN-104735984-A Use of anthranilamide compounds in soil and seed treatment application methods BASF SE 2015-06-24 CN disclosed
EP-2595985-A1 ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES Syngenta Participations AG (CH) 2013-05-29 EP disclosed
EP-2595984-A1 MICROBICIDES Syngenta Participations AG (CH) 2013-05-29 EP disclosed
WO-2012010568-A1 MICROBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-26 WO disclosed
WO-2012010567-A1 ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-26 WO disclosed