Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517024 | 0.80 | ALDH1A1 (0.62) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL19779319 | 0.77 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL19680104 | 0.77 | AKR1C3 (0.54) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL19680105 | 0.77 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL678299 | 0.77 | ALDH1A1 (1.00) | PTGS1PTGS2MAPTALDH1A1MEN1 | |
| SCHEMBL1966415 | 0.74 | KDM1A (0.48) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL18607707 | 0.73 | KCNK3 (0.69) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL21488823 | 0.72 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS1PTGS2TAS2R14 | |
| SCHEMBL31002670 | 0.71 | MEN1 (0.68) | PTGS1PTGS2MAPTALDH1A1MEN1 | |
| SCHEMBL1118619 | 0.71 | MEN1 (0.68) | PTGS1PTGS2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376384-B2 | Diaryliodonium salt | UBE INDUSTRIES, LTD. (JP) | 2016-06-28 | — | — | US | disclosed |
| US-20160046566-A1 | DIARYLIODONIUM SALT | UBE INDUSTRIES, LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046566-A1 | DIARYLIODONIUM SALT | AGTR2, KCNA5, AGTR1 | AKR1C3 597/4885AKR1C2 421/4885PTGS1 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.