Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19680104 | 0.78 | AKR1C3 (0.54) | AKR1C3AKR1C2PTGS2PTGS1TAS2R14 | |
| SCHEMBL19779319 | 0.78 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS2PTGS1TAS2R14 | |
| SCHEMBL17517023 | 0.77 | AKR1C3 (0.67) | AKR1C3AKR1C2PTGS2PTGS1TAS2R14 | |
| SCHEMBL19680103 | 0.76 | AKR1C3 (0.49) | AKR1C3AKR1C2PTGS2PTGS1TAS2R14 | |
| SCHEMBL219895 | 0.75 | TDP1 (0.61) | PTGS2LMNATDP1IDO1CYP1A2 | |
| SCHEMBL1966415 | 0.75 | KDM1A (0.48) | AKR1C3AKR1C2PTGS2PTGS1TAS2R14 | |
| SCHEMBL29643291 | 0.75 | CYP3A4 (0.52) | AKR1C3AKR1C2LMNATDP1CYP3A4 | |
| SCHEMBL1633970 | 0.75 | CYP3A4 (0.52) | AKR1C3AKR1C2LMNATDP1CYP3A4 | |
| SCHEMBL21488823 | 0.74 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS2PTGS1TAS2R14 | |
| SCHEMBL18129235 | 0.72 | LMNA (0.43) | AKR1C3AKR1C2PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159544-A1 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2023077125-A2 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TERRAN BIOSCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-107108490-B | Method for producing nitrogen-containing pentafluorosulfanylbenzene compound | 宇部兴产株式会社 | 2019-12-31 | — | — | CN | disclosed |
| US-9868701-B2 | Method for producing nitrogen-containing pentafluorosulfanylbenzene compound | UBE INDUSTRIES, LTD. (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9868701-B2 | Method for producing nitrogen-containing pentafluorosulfanylbenzene compound | UBE INDUSTRIES, LTD. (JP) | 2018-01-16 | — | — | US | disclosed |
| US-20170349545-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING PENTAFLUOROSULFANYLBENZENE COMPOUND | UBE CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20170349545-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING PENTAFLUOROSULFANYLBENZENE COMPOUND | UBE CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349545-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING PENTAFLUOROSULFANYLBENZENE COMPOUND | NPM1, PYM1, FPR2 | AKR1C3 1630/4885AKR1C2 2794/4885PTGS2 1608/4885 |
| US-20230159544-A1 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TPH2, TPH1, SLC18A2 | AKR1C3 3177/4885AKR1C2 2110/4885PTGS2 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.