Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849603 | 0.88 | LMNA (0.77) | LMNAKDM4EL3MBTL1PLA2G1BPOLB | |
| SCHEMBL7278068 | 0.88 | LMNA (0.77) | LMNAKDM4EL3MBTL1PLA2G1BPOLB | |
| SCHEMBL2289990 | 0.88 | LMNA (0.77) | LMNAKDM4EL3MBTL1PLA2G1BPOLB | |
| SCHEMBL16596122 | 0.84 | ADRB2 (0.71) | KDM4EL3MBTL1ADRB2 | |
| SCHEMBL7118929 | 0.84 | ADRB2 (0.71) | KDM4EL3MBTL1ADRB2 | |
| SCHEMBL28582068 | 0.84 | ADRB2 (0.71) | KDM4EL3MBTL1ADRB2 | |
| SCHEMBL4351380 | 0.83 | LMNA (0.71) | LMNAKDM4EL3MBTL1PLA2G1BPOLB | |
| Hydrochloric Acid SCHEMBL1405554 | 0.83 | ADRB2 (0.69) | LMNAKDM4EL3MBTL1ADRB2 | |
| Hydrochloric Acid SCHEMBL28435050 | 0.83 | ADRB2 (0.69) | LMNAKDM4EL3MBTL1ADRB2 | |
| Hydrochloric Acid SCHEMBL28662709 | 0.83 | ADRB2 (0.69) | LMNAKDM4EL3MBTL1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |