SCHEMBL17520394

SCHEMBL17520394

CCC/C=C/CCS(=O)(=O)NC(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
PPARA Q07869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17520388 0.88 ALDH1A1 (0.33)
SCHEMBL15870829 0.82 PPARG (0.32) PPARA
SCHEMBL805360 0.78 ACACB (0.37)
SCHEMBL10106473 0.74 HPGD (0.38) FAAH
SCHEMBL22369907 0.73 TAS1R3 (0.32) TAS1R3TAS1R1
SCHEMBL17520403 0.73 ALDH1A1 (0.32)
SCHEMBL8906669 0.72 CA2 (0.44) FAAH
SCHEMBL16000097 0.71 CA2 (0.47) FAAH
SCHEMBL17520384 0.71 CA2 (0.47) FAAH
SCHEMBL19776090 0.71 CA2 (0.47) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160039788-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS UNIVERSITY OF SOUTHERN CALIFORNIA 2016-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160039788-A1 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, TYMP, DPYD FAAH 2323/4885TAS1R3 4654/4885TAS1R1 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.