Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169881 | 0.92 | STING1 (0.50) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL16016991 | 0.88 | ALDH1A1 (0.55) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15450265 | 0.83 | STING1 (0.43) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15450261 | 0.83 | STING1 (0.43) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17358236 | 0.83 | STING1 (0.42) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17358246 | 0.83 | STING1 (0.42) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL16016989 | 0.83 | PDE4A (0.42) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17358245 | 0.83 | STING1 (0.42) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL16017082 | 0.82 | STING1 (0.42) | STING1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL16017066 | 0.82 | XDH (0.46) | STING1MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975869-B2 | Analogues of epicatechin and related polyphenols | SPHAERA PHARMA PVT. LTD. (IN) | 2018-05-22 | — | — | US | disclosed |
| US-20160039781-A1 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | SPHAERA PHARMA PVT. LTD. (SG) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039781-A1 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | PGC, TEAD3, TEAD4 | STING1 4635/4885MEN1 4171/4885MAPT 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.