Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 5/20 | 0.41 |
| ▸ | FPR2 | P25090 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482507 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4FPR1FPR2 | |
| SCHEMBL6482499 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4FPR1FPR2 | |
| SCHEMBL6482502 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4FPR1FPR2 | |
| SCHEMBL10637116 | 0.78 | FPR1 (0.41) | SLC6A3SLC6A2SLC6A4FPR1FPR2 | |
| SCHEMBL10642253 | 0.78 | HTT (0.44) | FPR1FPR2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10636994 | 0.77 | FPR1 (0.42) | SLC6A3SLC6A4FPR1FPR2 | |
| SCHEMBL10642709 | 0.75 | FPR1 (0.37) | FPR1FPR2TP53GPBAR1 | |
| SCHEMBL16065869 | 0.73 | HTT (0.47) | ALDH1A1MAPTKMT2ATP53MEN1 | |
| SCHEMBL8442229 | 0.71 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4ALDH1A1MAPT | |
| SCHEMBL16055833 | 0.71 | ALDH1A1 (0.46) | SLC6A3SLC6A2SLC6A4FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | SLC6A3 4548/4885SLC6A2 4247/4885SLC6A4 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.