Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17518313 | 0.87 | TSHR (0.31) | NPSR1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17524660 | 0.82 | ALDH1A1 (0.33) | TRPV1TRPA1ALDH1A1MAPTKDM5A | |
| SCHEMBL1709990 | 0.78 | CA2 (0.44) | SPHK1GPR84 | |
| SCHEMBL17518370 | 0.76 | TRPV1 (0.34) | SPHK1TRPV1TRPA1ALDH1A1MAPT | |
| SCHEMBL29171486 | 0.75 | SIGMAR1 (0.47) | SIGMAR1PLA2G1BPLA2G2APAOXL3MBTL1 | |
| SCHEMBL17518381 | 0.75 | LMNA (0.48) | ALDH1A1LMNA | |
| SCHEMBL19634478 | 0.72 | KDM4E (0.50) | PAOXTRPV1TRPA1ALDH1A1 | |
| SCHEMBL4312640 | 0.72 | PAOX (0.52) | NPSR1PAOXALDH1A1KDM5AKDM4C | |
| SCHEMBL29565670 | 0.72 | PAOX (0.52) | NPSR1PAOXALDH1A1KDM5AKDM4C | |
| SCHEMBL29564926 | 0.72 | PAOX (0.52) | NPSR1PAOXALDH1A1KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266927-B2 | Cyclosporin A analogs | ALLERGAN, INC. (US) | 2016-02-23 | — | — | US | disclosed |