Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011570 | 0.87 | MAPK1 (0.41) | ALDH1A1MAPK1NPC1TP53MAPT | |
| SCHEMBL1935994 | 0.84 | PLK1 (0.40) | ALDH1A1MAPK1NPC1TP53MAPT | |
| SCHEMBL15932340 | 0.81 | TDP1 (0.40) | NPC1CDC7DBF4GABRPGABRD | |
| SCHEMBL26910765 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPK1NPC1TP53MAPT | |
| SCHEMBL1934223 | 0.80 | FAAH (0.42) | ALDH1A1MAPK1NPC1TP53MAPT | |
| SCHEMBL20020154 | 0.79 | KDM4E (0.41) | KDM4E | |
| SCHEMBL553924 | 0.78 | KLKB1 (0.48) | ALDH1A1NPSR1HSD17B10CDC7DBF4 | |
| SCHEMBL13545976 | 0.77 | CA1 (0.42) | ALDH1A1MAPK1NPC1TP53MAPT | |
| SCHEMBL15551494 | 0.76 | LMNA (0.44) | ALDH1A1MAPK1TP53HTTHSD17B10 | |
| SCHEMBL754056 | 0.76 | ALDH1A1 (0.46) | ALDH1A1NPC1MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445702-B2 | Zinc binding compounds and their method of use | Life Technologies Corporation (US) | 2013-05-21 | — | — | US | disclosed |
| US-20110159517-A1 | Zinc binding compounds and their method of use | Life Technologies Corporation (US) | 2011-06-30 | — | — | US | disclosed |
| US-20090181364-A1 | ZINC BINDING COMPOUNDS AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-20050250214-A1 | Zinc binding compounds and their method of use | MOLECULAR PROBES, INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110159517-A1 | Zinc binding compounds and their method of use | SLC30A6, SLC30A7, SLC39A11 | ALDH1A1 3563/4885MAPK1 4727/4885NPC1 529/4885 |
| US-20050250214-A1 | Zinc binding compounds and their method of use | SLC30A6, SLC30A7, SLC39A11 | ALDH1A1 3599/4885MAPK1 4710/4885NPC1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.