Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17522829 | 0.79 | ACVRL1 (0.40) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL17525276 | 0.77 | SMN1; SMN2 (0.58) | KDM4EALDH1A1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL17525288 | 0.74 | KDM4E (0.45) | TP53KDM4EALDH1A1L3MBTL1POLB | |
| SCHEMBL18287259 | 0.74 | GAA (0.40) | TP53MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL28518676 | 0.72 | MAPK14 (0.41) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL19844386 | 0.70 | MAPK14 (0.41) | TP53MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL17522830 | 0.67 | P2RX4 (0.42) | TP53KDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1572546 | 0.67 | HSD17B10 (0.60) | TP53ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL13828515 | 0.67 | MAPT (0.53) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL27718637 | 0.67 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | AHR, CDYL, SLC18A1 | TP53 3167/4885MAPK13 2155/4885MAPK12 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.