Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081660 | 1.00 | BAZ2B (0.40) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL13377540 | 1.00 | BAZ2B (0.40) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL10819299 | 1.00 | BAZ2B (0.40) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL17525893 | 0.98 | BAZ2B (0.41) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL21386759 | 0.93 | BAZ2B (0.38) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL10313033 | 0.89 | BAZ2B (0.42) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL6370890 | 0.89 | BAZ2B (0.42) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL12395230 | 0.89 | BAZ2B (0.42) | BAZ2BHTTHPGDNCOA1NCOA3 | |
| SCHEMBL13917370 | 0.85 | HTT (0.34) | BAZ2BHTT | |
| SCHEMBL13862842 | 0.82 | HTT (0.32) | BAZ2BHTTCHEK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976347-B1 | METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE | MCFARLAND SHERRI ANN (US) | 2022-01-19 | — | — | EP | disclosed |
| US-9676806-B2 | Metal-based thiophene photodynamic compounds and their use | MCFARLAND SHERRI ANN (CA) | 2017-06-13 | — | — | US | disclosed |
| US-20160229878-A1 | METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE | MCFARLAND SHERRI ANN (CA) | 2016-08-11 | — | — | US | disclosed |
| US-9345769-B2 | Metal-based thiophene photodynamic compounds and their use | MCFARLAND SHERRI ANN (CA) | 2016-05-24 | — | — | US | disclosed |
| US-20160039854-A1 | METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE | MCFARLAND SHERRI ANN (CA) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229878-A1 | METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE | TP53, PPOX, HMBS | BAZ2B 416/4885HTT 2502/4885HPGD 993/4885 |
| US-20160039854-A1 | METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE | PIN1, PPIF, PPOX | BAZ2B 206/4885HTT 2408/4885HPGD 1908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.