Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525955 | 0.88 | ESR1 (0.47) | CYP19A1ESR1ESR2MEN1MAPK1 | |
| SCHEMBL17525950 | 0.81 | CYP19A1 (0.36) | CYP19A1STS | |
| SCHEMBL17525983 | 0.79 | MAPT (0.44) | CYP19A1ESR1ESR2MEN1MAPK1 | |
| SCHEMBL17525967 | 0.78 | SHBG (0.53) | CYP19A1ESR1ESR2MEN1MAPK1 | |
| SCHEMBL29470239 | 0.78 | ESR1 (0.61) | CYP19A1ESR1ESR2MEN1MAPK1 | |
| SCHEMBL14048666 | 0.77 | LMNA (0.56) | ESR1ESR2MEN1MAPK1KMT2A | |
| SCHEMBL14048707 | 0.77 | SHBG (0.49) | CYP19A1ESR1ESR2MEN1MAPK1 | |
| SCHEMBL13951923 | 0.77 | STS (0.72) | CYP19A1ESR1ESR2LMNAMAPT | |
| SCHEMBL2758352 | 0.75 | CYP19A1 (0.56) | CYP19A1ESR1ESR2MEN1MAPK1 | |
| SCHEMBL13952155 | 0.74 | STS (0.46) | CYP19A1ESR1ESR2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147014-B1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECH INC (CA) | 2016-02-17 | — | — | EP | disclosed |