Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.50 |
| ▸ | CTSL | P07711 | 13/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530335 | 0.90 | CTSS (0.55) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529981 | 0.89 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530013 | 0.88 | CTSL (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530239 | 0.87 | CTSL (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529971 | 0.84 | CTSS (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530188 | 0.83 | CTSS (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17529978 | 0.82 | CTSS (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530365 | 0.81 | CTSS (0.47) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530194 | 0.80 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL17530402 | 0.80 | CTSS (0.52) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |