Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529971 | 0.91 | CTSS (0.56) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17530248 | 0.89 | CTSL (0.59) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17530013 | 0.89 | CTSL (0.56) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17530194 | 0.89 | CTSS (0.52) | CTSLCTSSCTSBCTSKRAB9A | |
| SCHEMBL17529978 | 0.88 | CTSS (0.49) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17530170 | 0.88 | CTSS (0.51) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17529973 | 0.87 | CTSS (0.50) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17530365 | 0.86 | CTSS (0.47) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17530402 | 0.85 | CTSS (0.52) | CTSLCTSSCTSBCTSK | |
| SCHEMBL17529981 | 0.85 | CTSS (0.48) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |