Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.63 |
| ▸ | CTSS | P25774 | 6/20 | 0.54 |
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530007 | 0.91 | CTSL (0.62) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17529992 | 0.88 | CTSL (0.54) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17530229 | 0.85 | CTSL (0.50) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17530248 | 0.85 | CTSL (0.59) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17530002 | 0.83 | CTSL (0.52) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17529991 | 0.80 | CTSL (0.61) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17530364 | 0.80 | CTSB (0.64) | CTSSCTSKCTSB | |
| SCHEMBL17530181 | 0.79 | CTSL (0.52) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17530911 | 0.78 | CTSL (0.58) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7395983 | 0.77 | CTSS (0.67) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |