Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 18/20 | 0.54 |
| ▸ | CTSK | P43235 | 12/20 | 0.54 |
| ▸ | CTSS | P25774 | 11/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530181 | 0.91 | CTSL (0.52) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17529985 | 0.88 | CTSL (0.63) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530007 | 0.88 | CTSL (0.62) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530169 | 0.85 | CTSS (0.56) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530922 | 0.81 | CTSL (0.57) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530229 | 0.78 | CTSL (0.50) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530002 | 0.78 | CTSL (0.52) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530911 | 0.76 | CTSL (0.58) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530170 | 0.76 | CTSS (0.51) | CTSLCTSKCTSSCTSB | |
| SCHEMBL17530364 | 0.76 | CTSB (0.64) | CTSKCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |