Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529566 | 0.86 | S1PR1 (0.32) | — | |
| SCHEMBL17018436 | 0.83 | POLB (0.35) | CNR2 | |
| SCHEMBL24736809 | 0.83 | KIT (0.35) | — | |
| SCHEMBL25885815 | 0.83 | SIGMAR1 (0.36) | BRD4SIGMAR1CNR2 | |
| SCHEMBL30958298 | 0.82 | DDR1 (0.35) | CNR2 | |
| SCHEMBL20547490 | 0.82 | CNR2 (0.33) | CNR2 | |
| SCHEMBL17832758 | 0.82 | KCNH2 (0.36) | CNR2 | |
| SCHEMBL22683359 | 0.82 | DDR1 (0.35) | CNR2 | |
| SCHEMBL30958294 | 0.82 | CNR2 (0.33) | CNR2 | |
| SCHEMBL30958306 | 0.82 | PTGS2 (0.33) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183245-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-26 | — | — | EP | disclosed |
| US-10081641-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-25 | — | — | US | disclosed |
| US-20170260214-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-14 | — | — | US | disclosed |
| US-20170260214-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-14 | — | — | US | disclosed |
| US-20170260214-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-14 | — | — | US | disclosed |
| WO-2016026848-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081641-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | BRD4 4237/4885SIGMAR1 492/4885CNR2 1340/4885 |
| US-20170260214-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | BRD4 4237/4885SIGMAR1 492/4885CNR2 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.