Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.48 |
| ▸ | CTSB | P07858 | 11/20 | 0.40 |
| ▸ | CTSS | P25774 | 9/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CALCA | P06881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530393 | 0.89 | CTSL (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17529980 | 0.88 | CTSS (0.54) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17530391 | 0.86 | CTSB (0.54) | CTSBCTSSCTSK | |
| SCHEMBL17530392 | 0.83 | CTSL (0.53) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL17529990 | 0.83 | CTSL (0.60) | CTSLCTSBCTSSCTSKCHRM4 | |
| SCHEMBL17530188 | 0.78 | CTSS (0.49) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17530370 | 0.77 | CTSS (0.57) | CTSLCTSBCTSSCTSKCHRM4 | |
| SCHEMBL17529977 | 0.77 | CTSS (0.52) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17530361 | 0.76 | CTSB (0.55) | CTSBCTSSCTSK | |
| SCHEMBL17530002 | 0.74 | CTSL (0.52) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |