Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405849 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LTA4HPOLBKDM4EACHE | |
| SCHEMBL16215682 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LTA4HPOLBHRH3ACHE | |
| SCHEMBL24135043 | 0.84 | POLB (0.44) | ALDH1A1POLBKDM4EHRH3TSHR | |
| SCHEMBL3146950 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LTA4HPOLBKDM4EHRH3 | |
| SCHEMBL1427504 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LTA4HPOLBKDM4EHRH3 | |
| SCHEMBL29147689 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LTA4HPOLBKDM4EHRH3 | |
| SCHEMBL17055247 | 0.82 | LTA4H (0.54) | ALDH1A1LTA4HPOLBKDM4ETSHR | |
| SCHEMBL18557 | 0.82 | LTA4H (0.54) | ALDH1A1LTA4HPOLBKDM4ETSHR | |
| SCHEMBL6708193 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LTA4HKDM4EHRH3CHEK1 | |
| SCHEMBL13646584 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LTA4HKDM4EHRH3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029004-A1 | METHODS OF TREATING MULTIPLE MYELOMA WITH IMMUNOMODULATORY COMPOUNDS IN COMBINATION WITH ANTIBODIES | CELGENE CORPORATION (US) | 2016-02-25 | — | — | WO | disclosed |