Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20879548 | 0.91 | LMNA (0.42) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL15075492 | 0.90 | ALDH1A1 (0.39) | SMN1; SMN2P2RY6TK1 | |
| SCHEMBL25399418 | 0.87 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL25400298 | 0.83 | LMNA (0.44) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL7208634 | 0.80 | LMNA (0.38) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL17512825 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL17512823 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL15074352 | 0.79 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL22110554 | 0.78 | LMNA (0.43) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL22666161 | 0.78 | LMNA (0.43) | LMNASMN1; SMN2MAPTESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016028866-A1 | 2'-CHLORO AMINOPYRIMIDINONE AND PYRIMIDINE DIONE NUCLEOSIDES | GILEAD SCIENCES, INC. (US) | 2016-02-25 | — | — | WO | disclosed |