Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536178 | 1.00 | MAPT (0.41) | MAPTTHRBGSK3BLMNAATM | |
| SCHEMBL28509017 | 0.76 | MAPT (0.46) | MAPTTHRBGSK3BLMNAATM | |
| SCHEMBL4879128 | 0.73 | THRB (0.50) | MAPTTHRBGSK3BATMAKR1C3 | |
| SCHEMBL490213 | 0.73 | THRB (0.50) | MAPTTHRBGSK3BATMAKR1C3 | |
| SCHEMBL4906426 | 0.73 | THRB (0.50) | MAPTTHRBGSK3BATMAKR1C3 | |
| SCHEMBL5799213 | 0.73 | MAPT (0.51) | MAPTTHRBGSK3BLMNAATM | |
| SCHEMBL16266991 | 0.72 | THRB (0.49) | MAPTTHRBGSK3BATMAKR1C3 | |
| SCHEMBL8153615 | 0.71 | CYP1A2 (0.52) | MAPTTHRBGSK3BATMAKR1C3 | |
| SCHEMBL600723 | 0.70 | LMNA (0.52) | MAPTTHRBGSK3BLMNAATM | |
| SCHEMBL600722 | 0.70 | LMNA (0.52) | MAPTTHRBGSK3BLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060379-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | E INK CORPORATION | 2016-03-03 | — | — | US | disclosed |