Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836340 | 0.83 | DRD2 (0.37) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| Iodide SCHEMBL11409935 | 0.81 | DRD2 (0.36) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| SCHEMBL4879848 | 0.81 | ADRA1D (0.35) | DRD2ADRA1AMEN1MAPK1KMT2A | |
| Iodide SCHEMBL11439990 | 0.80 | ADRA1D (0.34) | DRD2ADRA1AALDH1A1 | |
| SCHEMBL4405530 | 0.78 | PIM1 (0.41) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| SCHEMBL5668191 | 0.78 | KDM4E (0.40) | HTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL16766572 | 0.78 | P2RX4 (0.34) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| SCHEMBL28623415 | 0.78 | DRD2 (0.34) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| SCHEMBL31202626 | 0.77 | KDM4E (0.42) | FAAHHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9158078 | 0.77 | KDM4E (0.42) | FAAHHTR1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027089-A1 | QUINOLIUM CONJUGATES OF CYCLOSPORIN | UCL BUSINESS PLC (GB) | 2016-02-25 | — | — | WO | disclosed |