Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27629725 | 0.98 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BCASP3DRD2 | |
| Hydrochloric Acid SCHEMBL27639967 | 0.98 | DRD2 (0.34) | ADRA1DADRA1AADRA1BCASP3DRD2 | |
| Iodide SCHEMBL11439990 | 0.98 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BCASP3DRD2 | |
| SCHEMBL17536192 | 0.81 | FAAH (0.36) | ADRA1ADRD2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL14313918 | 0.80 | MAPK1 (0.32) | ADRA1ADRD2ALDH1A1LMNAMAPT | |
| SCHEMBL29128835 | 0.78 | MAPK1 (0.33) | ADRA1ADRD2ALDH1A1LMNAKMT2A | |
| SCHEMBL27914484 | 0.78 | P2RX4 (0.33) | LMNATSHR | |
| SCHEMBL3714615 | 0.77 | MAPT (0.38) | L3MBTL1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL10760089 | 0.77 | CHRM2 (0.38) | ADRA1ADRD2ALDH1A1LMNAMAPT | |
| SCHEMBL29486049 | 0.77 | MAPT (0.38) | L3MBTL1ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981495-A | OXIDATION RESISTANCE, (POLY)-1,2-DIHYDROQUINOLINE | BETZ LABORATORIES, INC. (US) | 1991-01-01 | — | — | US | claimed |
| US-4941968-A | ALKYL-1,2-HIHYDROQUINOLINE COMPOUNDS TO INHIBIT GUM FORMATION | BETZ LABORATORIES, INC. (US) | 1990-07-17 | — | — | US | claimed |
| US-11390586-B2 | Pyridinium, quinolinium, acridinium, pyrylium, chromenylium or xanthylizum reactive desorption and/or laser ablation ionization matrices and use thereof | ANDREN PER (SE) | 2022-07-19 | — | — | US | disclosed |
| EP-3762374-A1 | PYRIDINIUM, QUINOLINIUM, ACRIDINIUM, PYRYLIUM, CHROMENYLIUM OR XANTHYLIZUM REACTIVE DESORPTION AND/OR LASER ABLATION IONIZATION MATRICES AND USE THEREOF | Andrén, Per (SE) | 2021-01-13 | — | — | EP | disclosed |
| US-20200407317-A1 | PYRIDINIUM, QUINOLINIUM, ACRIDINIUM, PYRYLIUM, CHROMENYLIUM OR XANTHYLIZUM REACTIVE DESORPTION AND/OR LASER ABLATION IONIZATION MATRICES AND USE THEREOF | ANDREN PER (SE) | 2020-12-31 | — | — | US | disclosed |
| CN-111971275-A | Pyridinium, quinolinium, acridinium, pyrylium, benzopyrylium or xanthylium reactive desorption and/or laser ablation ionization matrix and use thereof | 皮尔·安德伦 | 2020-11-20 | — | — | CN | disclosed |
| WO-2019172830-A1 | PYRIDINIUM, QUINOLINIUM, ACRIDINIUM, PYRYLIUM, CHROMENYLIUM OR XANTHYLIZUM REACTIVE DESORPTION AND/OR LASER ABLATION IONIZATION MATRICES AND USE THEREOF | ANDREN PER (SE) | 2019-09-12 | — | — | WO | disclosed |
| US-7470292-B2 | Mannich base derived from p-substituted phenols or cashew nut shell oil and aromatic diamine; sedimentation, corrosion and water uptake resistance | INDIAN OIL CORPORATION LIMITED (IN) | 2008-12-30 | — | — | US | disclosed |
| EP-0628424-B1 | Method for marking a surface of an object by means of a laser | KONINKL PHILIPS ELECTRONICS NV (NL) | 1998-11-04 | — | — | EP | disclosed |
| US-5783528-A | MIXTURE WITH ALKYLATED POLYAROMATIC COMPOUNDS | DIVERSEY LEVER, INC. (US) | 1998-07-21 | — | — | US | disclosed |
| US-5554196-A | Method of marking a surface of an object by means of a laser light | U.S. PHILIPS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0696634-A1 | Stabilization of gasoline and gasoline mixtures | EXXON CHEMICAL PATENTS INC. (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5446165-A | Crystalline 1-alkyl-2-quinolinium salts | ZENECA LIMITED (GB) | 1995-08-29 | — | — | US | disclosed |
| EP-0628424-A1 | Method for marking a surface of an object by means of a laser | Koninklijke Philips Electronics N.V. (NL) | 1994-12-14 | — | — | EP | disclosed |
| US-4981495-A | OXIDATION RESISTANCE, (POLY)-1,2-DIHYDROQUINOLINE | BETZ LABORATORIES, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4981495-A | OXIDATION RESISTANCE, (POLY)-1,2-DIHYDROQUINOLINE | BETZ LABORATORIES, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4941968-A | ALKYL-1,2-HIHYDROQUINOLINE COMPOUNDS TO INHIBIT GUM FORMATION | BETZ LABORATORIES, INC. (US) | 1990-07-17 | — | — | US | disclosed |
| US-4941968-A | ALKYL-1,2-HIHYDROQUINOLINE COMPOUNDS TO INHIBIT GUM FORMATION | BETZ LABORATORIES, INC. (US) | 1990-07-17 | — | — | US | disclosed |
| US-4229343-A | Azo dyes from an oxadiazolyl-substituted aniline | BASF AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |
| US-4016151-A | Phenyl-substituted phthalazone azo dyes with a coupling component of the phenol, napthol, acetoacetarylide, pyrazolone, quinolone, pyridine, pyrimidone or isoquinolone series | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11390586-B2 | Pyridinium, quinolinium, acridinium, pyrylium, chromenylium or xanthylizum reactive desorption and/or laser ablation ionization matrices and use thereof | KYNU, ANXA5, RAB35 | ADRA1D 3461/4885ADRA1A 3382/4885ADRA1B 2571/4885 |
| US-20200407317-A1 | PYRIDINIUM, QUINOLINIUM, ACRIDINIUM, PYRYLIUM, CHROMENYLIUM OR XANTHYLIZUM REACTIVE DESORPTION AND/OR LASER ABLATION IONIZATION MATRICES AND USE THEREOF | KYNU, ANXA5, RAB35 | ADRA1D 3461/4885ADRA1A 3382/4885ADRA1B 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.