Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | PFKFB2 | O60825 | 4/20 | 0.43 |
| ▸ | PFKFB1 | P16118 | 4/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536367 | 0.90 | PFKFB1 (0.42) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL17350060 | 0.87 | ALDH1A1 (0.46) | ARIMPDH2IMPDH1ALDH1A1MET | |
| SCHEMBL17536366 | 0.83 | MTNR1B (0.63) | ARIMPDH2ALDH1A1MTNR1BMTNR1A | |
| SCHEMBL13720420 | 0.80 | AR (0.52) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL12594169 | 0.80 | AR (0.52) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL1979562 | 0.78 | AR (0.55) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL29437996 | 0.78 | AR (0.55) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL21908141 | 0.77 | AR (0.54) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL21980927 | 0.77 | AR (0.48) | ARIMPDH2IMPDH1ALDH1A1MTNR1B | |
| SCHEMBL13721221 | 0.77 | AR (0.48) | ARIMPDH2IMPDH1ALDH1A1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058737-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | AUTIFONY THERAPEUTICS LIMITED (GB) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058737-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | KCND3, KCNK3, KCNA3 | AR 4780/4885IMPDH2 1230/4885IMPDH1 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.