Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737380 | 0.96 | CYP2C19 (0.41) | CYP2C19C5AR1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10295955 | 0.93 | CYP2C19 (0.35) | CYP2C19C5AR1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10128593 | 0.90 | CYP2C19 (0.42) | CYP2C19ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL17933061 | 0.89 | GAA (0.35) | CYP2C19C5AR1ALDH1A1CYP1A2TSHR | |
| SCHEMBL4885222 | 0.89 | ALDH1A1 (0.43) | CYP2C19ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1753727 | 0.88 | ALDH1A1 (0.39) | CYP2C19ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL462137 | 0.88 | HPRT1 (0.47) | ALDH1A1CYP1A2CYP3A4TDP1L3MBTL1 | |
| SCHEMBL15024795 | 0.87 | SIGMAR1 (0.47) | CYP2C19C5AR1ALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL2944852 | 0.87 | SIGMAR1 (0.47) | CYP2C19C5AR1ALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL2537763 | 0.86 | ALDH1A1 (0.42) | CYP2C19C5AR1ALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158835-B2 | Fluorene compound and organic electroluminescence device | CANON KABUSHIKI KAISHA (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158835-B2 | Fluorene compound and organic electroluminescence device | CANON KABUSHIKI KAISHA (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090200919-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090200919-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090200919-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | AFF1, LEF1, AFF2 | CYP2C19 251/4885C5AR1 3896/4885ALDH1A1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.