Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.60 |
| ▸ | ELANE | P08246 | 8/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | APOB | P04114 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537607 | 0.89 | NR3C2 (0.77) | NR3C2ELANEPDE7APDE4APOLB | |
| SCHEMBL18593496 | 0.88 | NR3C2 (0.77) | NR3C2ELANEPDE7APDE4ASMO | |
| SCHEMBL17493297 | 0.83 | NR3C2 (0.72) | NR3C2ELANEPDE7APDE4AHPGD | |
| SCHEMBL19414184 | 0.80 | NR3C2 (0.51) | NR3C2ELANEPDE7APDE4APOLB | |
| SCHEMBL1380377 | 0.78 | NR3C2 (0.67) | NR3C2PDE7APDE4ASMO | |
| SCHEMBL12296591 | 0.78 | NR3C2 (0.57) | NR3C2ELANEPDE7APDE4AHPGD | |
| SCHEMBL20306403 | 0.78 | NR3C2 (0.73) | NR3C2ELANEPDE7APDE4APOLB | |
| SCHEMBL19414196 | 0.77 | NR3C2 (0.48) | NR3C2ELANEPDE7APDE4APOLB | |
| SCHEMBL19255453 | 0.77 | NR3C2 (0.48) | NR3C2ELANEPDE7APDE4APOLB | |
| SCHEMBL19414250 | 0.76 | P2RX7 (0.36) | NR3C2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233341-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-9676713-B2 | Crystal of pyrrole derivative and method for producing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233341-A1 | CRYSTAL OF PYRROLE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | NR3C2, MC2R, CRHR1 | NR3C2 1/4885ELANE 2553/4885PDE7A 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.