Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 3/20 | 0.41 |
| ▸ | ATP4B | P51164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537645 | 1.00 | ADRA1A (0.46) | ADRA1AADRA1BCCNB2CDK1CCNB1 | |
| SCHEMBL17537646 | 0.94 | ATP4A (0.46) | ATP4AATP4BTDO2MEN1KMT2A | |
| SCHEMBL17537647 | 0.94 | ADRA1A (0.50) | ADRA1AADRA1BCCNB2CDK1CCNB1 | |
| SCHEMBL17537648 | 0.88 | ATP4A (0.42) | GSK3BATP4AATP4BTDO2MEN1 | |
| SCHEMBL25034152 | 0.81 | MEN1 (0.54) | ADRA1AADRA1BCCNB2CDK1CCNB1 | |
| SCHEMBL17537643 | 0.81 | NR4A2 (0.47) | GSK3BATP4AATP4BMEN1KMT2A | |
| SCHEMBL17537657 | 0.78 | KMT2A (0.63) | ATP4AATP4BMEN1KMT2AMAPT | |
| SCHEMBL22559142 | 0.75 | MEN1 (0.44) | TDO2MEN1KMT2AMAPTNR1I2 | |
| SCHEMBL29396458 | 0.75 | MEN1 (0.44) | TDO2MEN1KMT2AMAPTNR1I2 | |
| Dibromodeoxytopsentin SCHEMBL17537611 | 0.74 | ADRA1A (0.58) | ADRA1AADRA1BCCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023106-A1 | BIS-INDOLE ALKALOIDS FOR USE IN THE TREATMENT OF INFECTIONS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-02-18 | — | — | WO | disclosed |