Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6829216 | 0.98 | HPGD (0.51) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7353467 | 0.82 | HPGD (0.60) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5045391 | 0.79 | HPGD (0.53) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7537697 | 0.78 | HPGD (0.56) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5495002 | 0.78 | HPGD (0.66) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3223780 | 0.77 | HPGD (0.55) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL15178187 | 0.76 | HPGD (0.50) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL4775992 | 0.76 | HPGD (0.53) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1294785 | 0.76 | CTSK (0.50) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27847201 | 0.76 | HPGD (0.53) | HPGDALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455223-B2 | Reducing substituted alkanones such as 3-methylamino-1-(2-thienyl)-propan-1-one; biosynthesis; expression cassettes; host cells; for production of duloxetine | BASF SE (DE) | 2013-06-04 | — | — | US | claimed |
| US-20080220484-A1 | Novel Dehydrogenases, the Derivatives thereof, and Method for the Production of Optically Active Alkanols | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | claimed |
| EP-1929001-A1 | NOVEL DEHYDROGENASES, THE DERIVATIVES THEREOF, AND METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE ALKANOLS | BASF SE (DE) | 2008-06-11 | — | — | EP | claimed |
| EP-1613745-B1 | L-CARNITIN DEHYDROGENASES, THEIR DERIVATIVES AND METHOD FOR PRODUCING SUBSTITUTED (S) ALKANOLS | BASF SE (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2007033928-A1 | NOVEL DEHYDROGENASES, THE DERIVATIVES THEREOF, AND METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE ALKANOLS | BASF SE (DE) | 2007-03-29 | — | — | WO | claimed |
| US-20060211099-A1 | L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-21 | — | — | US | claimed |
| EP-1613745-A2 | L-CARNITIN DEHYDROGENASES, THEIR DERIVATIVES AND METHOD FOR PRODUCING SUBSTITUTED (S) ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-11 | — | — | EP | claimed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | claimed |
| WO-2004090094-A2 | L-CARNITIN DEHYDROGENASES, THEIR DERIVATIVES AND METHOD FOR PRODUCING SUBSTITUTED (S) ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | WO | claimed |
| CN-114790146-B | Preparation method of 3- (methylamino) -1-aryl acetone | 河南省科学院高新技术研究中心 | 2024-03-29 | — | — | CN | disclosed |
| CN-114790146-A | Preparation method of 3- (methylamino) -1-aryl acetone | 河南省科学院高新技术研究中心 | 2022-07-26 | — | — | CN | disclosed |
| CN-110964703-B | Enzyme for preparing intermediate of antidepressant duloxetine, biocatalysis method and application thereof | 南京朗恩生物科技有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-110951704-B | Alcohol dehydrogenase mutant with enhanced thermal stability and sequence thereof | 南京朗恩生物科技有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-110938609-B | Ketoreductase mutant with enhanced activity and application thereof | 南京朗恩生物科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20060211099-A1 | L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-21 | — | — | US | disclosed |
| WO-2006094945-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS BY MEANS OF ENZYMATIC REDUCTION | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-14 | — | — | WO | disclosed |
| CN-1771323-A | L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols | BASF AG (DE) | 2006-05-10 | — | — | CN | disclosed |
| EP-1613745-A2 | L-CARNITIN DEHYDROGENASES, THEIR DERIVATIVES AND METHOD FOR PRODUCING SUBSTITUTED (S) ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005108590-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS FROM ALKANONES USING A DEHYDROGENASE OF AZOARCUS | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-17 | — | — | WO | disclosed |
| WO-2004090094-A2 | L-CARNITIN DEHYDROGENASES, THEIR DERIVATIVES AND METHOD FOR PRODUCING SUBSTITUTED (S) ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220484-A1 | Novel Dehydrogenases, the Derivatives thereof, and Method for the Production of Optically Active Alkanols | ALDH7A1, ALDH3A1, ADH5 | HPGD 183/4885ALDH1A1 8/4885POLB 255/4885 |
| US-20060211099-A1 | L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols | ALDH7A1, ALDH3A1, AMPD3 | HPGD 346/4885ALDH1A1 16/4885POLB 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.