Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2612359 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1765338 | 0.81 | CXCR2 (0.50) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31486082 | 0.81 | CXCR2 (0.50) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7424567 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7425418 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL26345801 | 0.79 | PTPN1 (0.42) | TP53RXFP1AGTR1HTTLMNA | |
| SCHEMBL28282536 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27214503 | 0.77 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL17540401 | 0.76 | KDM5A (0.33) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28932597 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024071439-A1 | FUSED RING COMPOUND AND PHARMACEUTICAL CONTAINING SAME | 科研製薬株式会社 | 2024-04-04 | — | — | WO | disclosed |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-9718764-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | KDM4E 2761/4885ALDH1A1 2033/4885SMN1; SMN2 4493/4885 |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | KDM4E 2761/4885ALDH1A1 2033/4885SMN1; SMN2 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.