SCHEMBL17540463

SCHEMBL17540463

O=C(O/N=C(\CCC1CCCCC1)C(=O)c1ccc(Sc2ccc(C(=O)c3cccs3)cc2)cc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.40
KMT2A Q03164 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
HPGD P15428 4/20 0.39
PKM P14618 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 4/20 0.37
MAPT P10636 2/20 0.37
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
MEN1 O00255 3/20 0.35
LMNA P02545 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540444 0.88 L3MBTL1 (0.43) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17070003 0.88 L3MBTL1 (0.43) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17070001 0.87 L3MBTL1 (0.44) KMT2ANPC1RAB9APKMSMN1; SMN2
SCHEMBL19795438 0.87 L3MBTL1 (0.44) KMT2ANPC1RAB9APKMSMN1; SMN2
SCHEMBL25373230 0.87 L3MBTL1 (0.44) KMT2ANPC1RAB9APKMSMN1; SMN2
SCHEMBL17545816 0.85 SMN1; SMN2 (0.38) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17540464 0.85 KMT2A (0.50) KMT2ANPC1RAB9APKMSMN1; SMN2
SCHEMBL17540459 0.83 KMT2A (0.39) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17540458 0.83 ALDH1A1 (0.39) KMT2ANPC1RAB9APKMSMN1; SMN2
SCHEMBL17545815 0.82 KMT2A (0.37) KMT2ANPC1RAB9APKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed