Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057194 | 0.75 | MAPK1 (0.53) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL28031798 | 0.74 | MAPK1 (0.45) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL27828829 | 0.72 | HCAR1 (0.47) | ALDH1A1TDP1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL30198949 | 0.67 | TDP1 (0.60) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL230874 | 0.67 | TDP1 (0.60) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL30110487 | 0.67 | MAPK1 (0.60) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL373368 | 0.67 | MAPK1 (0.60) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL297021 | 0.67 | MAPK1 (0.60) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL30615522 | 0.67 | ALDH1A1 (0.59) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 | |
| SCHEMBL21463438 | 0.67 | ALDH1A1 (0.59) | ALDH1A1MAPK1TDP1L3MBTL1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186247-A1 | PROTEIN KINASE INHIBITORS | Astar Biotech LLC (US) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016029776-A1 | PROTEIN KINASE INHIBITORS | ASTAR BIOTECH LLC (US) | 2016-03-03 | — | — | WO | disclosed |