SCHEMBL1754268

SCHEMBL1754268

CO[Si](CCC(N)C1CCCCC1)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
DPP4 P27487 1/20 0.33
SHBG P04278 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
TP53 P04637 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3388586 0.84 DPP4 (0.33) EPHX1DPP4SHBGSIGMAR1TP53
SCHEMBL3724884 0.82 SHBG (0.35) EPHX1DPP4SHBGSIGMAR1
SCHEMBL28370484 0.79 EPHX1 (0.37) EPHX1DPP4SHBGSIGMAR1TP53
SCHEMBL10400142 0.78 EPHX1 (0.33) EPHX1DPP4SHBGSIGMAR1TP53
SCHEMBL2781157 0.75 EPHX1 (0.48) EPHX1DPP4SHBGSIGMAR1TP53
SCHEMBL28368845 0.72
SCHEMBL28515066 0.72
SCHEMBL29191106 0.72
SCHEMBL20319041 0.71 SHBG (0.46) EPHX1DPP4SHBGSIGMAR1TP53
SCHEMBL30142421 0.71 SHBG (0.46) EPHX1DPP4SHBGSIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113968958-B Polyurethane and preparation method and application thereof 广东富强科技股份有限公司 2023-11-21 CN claimed
WO-2023156368-A1 DRINKING CUPS MADE FROM CARDBOARD COATED WITH PRINTING LAYER AND CROSSLINKED POLYSILOXANE LAYER HUHTAMÄKI OYJ (FI) 2023-08-24 WO claimed
CN-109294318-A A kind of aqueous inorganic ceramic coating curing agent and preparation method thereof 湖南凯斯利新材料有限公司 2019-02-01 CN claimed
CN-109266057-A Extra-weather-proof high hard abrasion-resistance water inorganic nano ceramic coating of a kind of normal temperature cure and preparation method thereof 湖南凯斯利新材料有限公司 2019-01-25 CN claimed
CN-107298930-A A kind of preparation of organic silicon polyurea self stratifying coating and application method 江苏苏博特新材料股份有限公司 2017-10-27 CN claimed
EP-2970709-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES The Government of the United States of America, as represented by the Secretary of the Navy (US) 2016-01-20 EP claimed
WO-2014158535-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2014-10-02 WO claimed
JP-4469728-B2 2010-05-26 JP claimed
EP-2089445-A1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2009-08-19 EP claimed
EP-2089444-A1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2009-08-19 EP claimed
WO-2008043722-A1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2008-04-17 WO claimed
WO-2008043723-A1 RADIATION-CURABLE COMPOUNDS BASF SE (DE) 2008-04-17 WO claimed
JP-2006525134-A 2006-11-09 JP claimed
EP-1622729-A1 CORROSION PROTECTION ON METALS Degussa AG (DE) 2006-02-08 EP claimed
WO-2004098795-A1 CORROSION PROTECTION ON METALS DEGUSSA AG (DE) 2004-11-18 WO claimed
US-6492482-B2 WEAR AND CHEMICAL RESISTANCE DEGUSS-HUELS AKTIENGESELLSCHAFT (DE) 2002-12-10 US claimed
US-20020103286-A1 Cross-linking agents and thermosetting paints DEGUSSA AG (DE) 2002-08-01 US claimed
EP-1211273-A1 Crosslinker and heatcurable lacquers Degussa AG (DE) 2002-06-05 EP claimed
US-20020042471-A1 Nonaqueous, heat-curable two-component coating DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2002-04-11 US claimed
EP-1193278-A1 Non aqueous, heat curable, two component coating composition Degussa AG (DE) 2002-04-03 EP claimed