Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370484 | 0.82 | EPHX1 (0.37) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL3388586 | 0.80 | DPP4 (0.33) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL1754268 | 0.78 | EPHX1 (0.33) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL3724884 | 0.75 | SHBG (0.35) | EPHX1DPP4SHBGSIGMAR1 | |
| SCHEMBL2781157 | 0.75 | EPHX1 (0.48) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL21099017 | 0.74 | SIGMAR1 (0.38) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL30142421 | 0.71 | SHBG (0.46) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL7104978 | 0.71 | SHBG (0.46) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL20319041 | 0.71 | SHBG (0.46) | EPHX1DPP4SHBGSIGMAR1TP53 | |
| SCHEMBL3834490 | 0.71 | EPHX1 (0.44) | EPHX1DPP4SHBGSIGMAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892918-A | TOUGHENING THERMOSETTING MATRIX RESINS | BASF CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| US-4847154-A | Thermosetting resin systems containing secondary amine-terminated siloxane modifiers | BASF CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0312771-A1 | Thermosetting resin systems containing secondary amine-terminated siloxane modifiers | BASF Aktiengesellschaft (DE) | 1989-04-26 | — | — | EP | disclosed |