SCHEMBL28370484

SCHEMBL28370484

C[Si](C)(C)CCC(N)C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.37
SHBG P04278 1/20 0.37
DPP4 P27487 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21099017 0.86 SIGMAR1 (0.38) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL10400142 0.82 EPHX1 (0.33) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL3388586 0.81 DPP4 (0.33) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL21098976 0.79 SHBG (0.32) SHBG
SCHEMBL2781157 0.79 EPHX1 (0.48) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL1754268 0.79 EPHX1 (0.33) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL3724884 0.76 SHBG (0.35) EPHX1SHBGDPP4SIGMAR1
SCHEMBL20319041 0.76 SHBG (0.46) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL30142421 0.76 SHBG (0.46) EPHX1SHBGDPP4SIGMAR1TP53
SCHEMBL7104978 0.76 SHBG (0.46) EPHX1SHBGDPP4SIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734653-B Preparation method of chemical coating type hydrophobic white carbon black 浙江新纳材料科技股份有限公司 2021-03-26 CN claimed
CN-110734653-A Preparation method of chemically-coated hydrophobic white carbon black 浙江新纳材料科技股份有限公司 2020-01-31 CN claimed
CN-110734653-B Preparation method of chemical coating type hydrophobic white carbon black 浙江新纳材料科技股份有限公司 2021-03-26 CN disclosed
CN-110734653-A Preparation method of chemically-coated hydrophobic white carbon black 浙江新纳材料科技股份有限公司 2020-01-31 CN disclosed