SCHEMBL3388586

SCHEMBL3388586

CO[Si](C)(CCC(N)C1CCCCC1)OC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.33
EPHX1 P07099 1/20 0.32
SHBG P04278 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1754268 0.84 EPHX1 (0.33) DPP4EPHX1SHBGSIGMAR1TP53
SCHEMBL28370484 0.81 EPHX1 (0.37) DPP4EPHX1SHBGSIGMAR1TP53
SCHEMBL10400142 0.80 EPHX1 (0.33) DPP4EPHX1SHBGSIGMAR1TP53
SCHEMBL3724884 0.74 SHBG (0.35) DPP4EPHX1SHBGSIGMAR1
SCHEMBL2781157 0.73 EPHX1 (0.48) DPP4EPHX1SHBGSIGMAR1TP53
SCHEMBL21099017 0.73 SIGMAR1 (0.38) DPP4EPHX1SHBGSIGMAR1TP53
SCHEMBL17099908 0.71 SHBG (0.33) SHBG
SCHEMBL28006318 0.71 KDM4E (0.34) EPHX1TP53
SCHEMBL28102817 0.70
SCHEMBL30142421 0.70 SHBG (0.46) DPP4EPHX1SHBGSIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063991-A Medical magnesium alloy surface antibacterial corrosion-resistant coating and preparation method thereof 金陵科技学院 2024-05-24 CN claimed
CN-116206799-A Silane coupling agent modified silver coated copper powder heterojunction battery silver paste and preparation method thereof 四川东树新材料有限公司 2023-06-02 CN claimed
CN-115477529-A Concrete based on granite powder and preparation method thereof 保利长大工程有限公司 2022-12-16 CN claimed
CN-112961307-B Solvent-free polyurethane resin, impregnation slurry, and preparation method and application thereof 上海华峰新材料研发科技有限公司 2022-05-10 CN claimed
CN-111875988-A Modified needle-shaped wollastonite powder, preparation method and application thereof, and pipeline anticorrosion epoxy powder coating 江西广源化工有限责任公司 2020-11-03 CN claimed
CN-107974108-A Reactive organic hybrid inorganic nano silica finish and its preparation and application 鳄鱼制漆(上海)有限公司 2018-05-01 CN claimed
CN-101709148-B Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof NORTH AMERICA TEMIC INC 2014-11-12 CN claimed
CN-103333339-A Method for preparing hydroxyl-terminated phenyl amino polyether modified silicone oil HUANGSHAN QIANGLI CHEMICAL CO LTD 2013-10-02 CN claimed
CN-103333340-A Hydroxyl-terminated phenyl amino polyether modified silicone oil HUANGSHAN QIANGLI CHEMICAL CO LTD 2013-10-02 CN claimed
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US claimed
CN-102051120-A Super-hydrophobic coating material, preparation method thereof and super-hydrophobic coating HENKEL AG & CO KGAA 2011-05-11 CN claimed
CN-101892115-A Release agent and application thereof HENKEL CHINA INVEST CO LTD 2010-11-24 CN claimed
CN-101709148-A Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof NORTH AMERICA TEMIC INC 2010-05-19 CN claimed
CN-101705001-A A method of preparing amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof TEMIC AUTOMOTIVE NA INC 2010-05-12 CN claimed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
CN-118063991-A Medical magnesium alloy surface antibacterial corrosion-resistant coating and preparation method thereof 金陵科技学院 2024-05-24 CN disclosed
CN-116206799-A Silane coupling agent modified silver coated copper powder heterojunction battery silver paste and preparation method thereof 四川东树新材料有限公司 2023-06-02 CN disclosed
CN-101230138-A Aqueous siliconiting polymer emulsion as well as preparation method and use thereof HENKEL MAN AG (DE) 2008-07-30 CN disclosed
CN-1587293-A Process for preparing high solid single component polyurethane elastor and its use UNIV FUDAN (CN) 2005-03-02 CN disclosed