Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454493 | 1.00 | DNM1 (0.46) | DNM1SERPINE1FAAHTSHRTHRB | |
| SCHEMBL7160479 | 1.00 | DNM1 (0.46) | DNM1SERPINE1FAAHTSHRTHRB | |
| SCHEMBL17545124 | 0.90 | TDP1 (0.47) | SERPINE1FAAHTDP1CA1CA2 | |
| SCHEMBL12669289 | 0.80 | DNM1 (0.46) | DNM1FAAHTSHRTHRBCA1 | |
| SCHEMBL2127290 | 0.80 | DNM1 (0.46) | DNM1FAAHTSHRTHRBCA1 | |
| SCHEMBL11873535 | 0.79 | SERPINE1 (0.35) | DNM1SERPINE1FAAHTDP1MCHR1 | |
| SCHEMBL4666266 | 0.78 | CA1 (0.48) | SERPINE1TDP1CA1CA2CA9 | |
| SCHEMBL19846860 | 0.78 | FAAH (0.50) | DNM1SERPINE1FAAHTSHRTHRB | |
| SCHEMBL12967474 | 0.78 | DNM1 (0.50) | DNM1FAAHTSHRTHRB | |
| SCHEMBL12967471 | 0.78 | DNM1 (0.50) | DNM1FAAHTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165686-A1 | POLYURETHANE COMPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000053676-A1 | POLYURETHANE COMPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-09-14 | — | — | WO | disclosed |