SCHEMBL17545697

SCHEMBL17545697

C=Cc1ccc(S(=O)(=O)N(C)S(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
ATM Q13315 1/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 1/20 0.34
AGER Q15109 1/20 0.33
NR1H3 Q13133 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
MAPT P10636 1/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19389695 0.84 TDP1 (0.55) TDP1ATMALDH1A1LMNAMEN1
SCHEMBL17545747 0.81 TDP1 (0.40) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL12674241 0.80 AGER (0.53) ATMLMNAGAAAGERHTT
SCHEMBL25525233 0.78 CA1 (0.42) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL25681971 0.77 TDP1 (0.41) TDP1ATMALDH1A1LMNAMEN1
SCHEMBL1494554 0.77 TDP1 (0.55) TDP1ATMALDH1A1LMNAMEN1
SCHEMBL12674245 0.74 NR1H3 (0.52) NR1H3CA12CA1CA2CA9
SCHEMBL20906806 0.73 TDP1 (0.55) TDP1ALDH1A1LMNAMEN1KMT2A
SCHEMBL942014 0.73 TDP1 (0.41) TDP1ALDH1A1
SCHEMBL25525227 0.71 GAA (0.69) ATMALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200259094-A1 CONDUCTIVE POLYMER COMPOSITE AND CONDUCTIVE POLYMER COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-13 US disclosed
US-20200247926-A1 POLYMERIZABLE MONOMER, POLYMER COMPOUND FOR CONDUCTIVE POLYMER, AND METHOD FOR PRODUCING THE POLYMER COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-06 US disclosed
US-20160052877-A1 SALT, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200247926-A1 POLYMERIZABLE MONOMER, POLYMER COMPOUND FOR CONDUCTIVE POLYMER, AND METHOD FOR PRODUCING THE POLYMER COMPOUND HCN4, HCN2, HCN3 TDP1 3254/4885ATM 3686/4885ALDH1A1 2526/4885
US-20160052877-A1 SALT, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, AFF1, FRG1 TDP1 4562/4885ATM 3816/4885ALDH1A1 2206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.