SCHEMBL17545776

SCHEMBL17545776

Cc1cc(N=Nc2cc(C)c(N=Nc3c(S(=O)(=O)O)cc4cc(NC(=O)c5ccc(N)cc5)ccc4c3O)cc2C)c(C)cc1N=Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 12/20 0.55
PHLPP2 Q6ZVD8 3/20 0.53
CD40 P25942 1/20 0.51
CD40LG P29965 1/20 0.51
PRMT3 O60678 1/20 0.50
EP300 Q09472 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
PRMT1 Q99873 1/20 0.50
CASP6 P55212 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
GLO1 Q04760 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19235110 0.90 ENPP2 (0.56) ENPP2PHLPP2CD40CD40LGPRMT3
SCHEMBL17540335 0.90 PRMT3 (0.63) ENPP2PHLPP2CD40CD40LGPRMT3
SCHEMBL15935837 0.88 ENPP2 (0.57) ENPP2PHLPP2CD40CD40LGPRMT3
SCHEMBL12830344 0.88 CD40 (0.64) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19234925 0.88 CD40 (0.64) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL15935779 0.88 CD40 (0.64) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL14469829 0.88 ENPP2 (0.58) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL17540337 0.87 ENPP2 (0.56) ENPP2PHLPP2CD40CD40LGPRMT3
SCHEMBL19234835 0.87 ENPP2 (0.61) ENPP2PHLPP2CD40CD40LGPRMT3
SCHEMBL14388145 0.87 CD40 (0.61) ENPP2CD40CD40LGPRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10209418-B2 Achromatic polarization element, and polarization plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed