Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.58 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.55 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.55 |
| ▸ | LGALS4 | P56470 | 3/20 | 0.55 |
| ▸ | AMY2A | P04746 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23425692 | 1.00 | AMY1A (0.58) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL17547717 | 1.00 | AMY1A (0.58) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL17547716 | 1.00 | AMY1A (0.58) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL17547745 | 1.00 | AMY1A (0.58) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL17547723 | 1.00 | AMY1A (0.58) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL17742516 | 0.91 | AMY1A (0.64) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL18160887 | 0.91 | AMY1A (0.64) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL24434287 | 0.91 | AMY1A (0.64) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL22695695 | 0.91 | AMY1A (0.64) | AMY1ALGALS8LGALS3LGALS4AMY2A | |
| SCHEMBL769113 | 0.91 | AMY1A (0.64) | AMY1ALGALS8LGALS3LGALS4AMY2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181607-A1 | THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION | The University of the Regents of California (US) | 2023-06-15 | — | — | US | disclosed |
| US-20180111955-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-04-26 | — | — | US | disclosed |
| US-9856283-B2 | Thiosaccharide mucolytic agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160060284-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111955-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | MUC1, TREH, FUT6 | AMY1A 407/4885LGALS8 109/4885LGALS3 134/4885 |
| US-20160060284-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | MUC1, TREH, FUT6 | AMY1A 407/4885LGALS8 109/4885LGALS3 134/4885 |
| US-20230181607-A1 | THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION | TMPRSS4, ACE, ACE2 | AMY1A 1387/4885LGALS8 33/4885LGALS3 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.