Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19395990 | 0.93 | TAAR1 (0.41) | TAAR1SLC6A2SLC6A3SLC6A4MAOA | |
| SCHEMBL19396021 | 0.87 | ALOX5 (0.40) | TAAR1SLC6A2SLC6A3SLC6A4MAOA | |
| SCHEMBL17549006 | 0.87 | TAAR1 (0.38) | TAAR1SLC6A2SLC6A3SLC6A4MAOA | |
| SCHEMBL407650 | 0.78 | POLB (0.39) | — | |
| SCHEMBL1810429 | 0.73 | PNMT (0.51) | PNMT | |
| SCHEMBL14478276 | 0.72 | — | — | |
| SCHEMBL13692285 | 0.72 | — | — | |
| SCHEMBL2022682 | 0.72 | — | — | |
| SCHEMBL19396014 | 0.70 | POLB (0.36) | TAAR1CYP2A6 | |
| SCHEMBL17509731 | 0.70 | CHRM2 (0.39) | TAAR1SLC6A2SLC6A3SLC6A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364210-B2 | Diamine compounds, dinitro compounds and other compounds, and methods of producing thereof and uses related thereof | MICROMIDAS, INC. (US) | 2019-07-30 | — | — | US | disclosed |
| US-20170275236-A1 | DIAMINE COMPOUNDS, DINITRO COMPOUNDS AND OTHER COMPOUNDS, AND METHODS OF PRODUCING THEREOF AND USES RELATED THEREOF | MICROMIDAS, INC. (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2016033348-A1 | DIAMINE COMPOUNDS, DINITRO COMPOUNDS AND OTHER COMPOUNDS, AND METHODS OF PRODUCING THEREOF AND USES RELATED THEREOF | MICROMIDAS, INC. (US) | 2016-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275236-A1 | DIAMINE COMPOUNDS, DINITRO COMPOUNDS AND OTHER COMPOUNDS, AND METHODS OF PRODUCING THEREOF AND USES RELATED THEREOF | DDC, DDT, DAO | TAAR1 833/4885SLC6A2 1486/4885SLC6A3 1221/4885 |
| US-10364210-B2 | Diamine compounds, dinitro compounds and other compounds, and methods of producing thereof and uses related thereof | DDC, DDT, DAO | TAAR1 833/4885SLC6A2 1486/4885SLC6A3 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.