Sugi Predict

Sugi Predict / Compounds / SCHEMBL1810429

SCHEMBL1810429

SCHEMBL1810429

CC(N)Cc1ccc(-c2ccc(Cl)c(Cl)c2)o1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PNMT P11086 2/20 0.51
▸ ALDH1A1 P00352 5/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ HPGD P15428 4/20 0.42
▸ KMT2A Q03164 4/20 0.42
▸ RAB9A P51151 3/20 0.42
▸ MAPT P10636 3/20 0.42
▸ GAA P10253 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ THRB P10828 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ NPC1 O15118 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ FTO Q9C0B1 1/20 0.40
▸ AHR P35869 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ NPSR1 Q6W5P4 3/20 0.39
▸ HTT P42858 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1810953 0.98 PNMT (0.50) PNMTALDH1A1MEN1HPGDKMT2A
SCHEMBL1809210 0.83 KDM4E (0.54) PNMTALDH1A1MEN1HPGDKMT2A
SCHEMBL11832976 0.78 CYP3A4 (0.56) ALDH1A1MEN1HPGDKMT2ARAB9A
SCHEMBL1807289 0.76 ALDH1A1 (0.47) PNMTALDH1A1MEN1HPGDKMT2A
SCHEMBL13809594 0.75 MEN1 (0.54) ALDH1A1MEN1HPGDKMT2ARAB9A
SCHEMBL12075896 0.75 AHR (0.46) ALDH1A1MEN1HPGDKMT2ARAB9A
Hydrochloric Acid SCHEMBL1806909 0.74 ALDH1A1 (0.46) PNMTALDH1A1MEN1HPGDKMT2A
SCHEMBL17548872 0.73 TAAR1 (0.46) PNMT
SCHEMBL11810011 0.72 KMT2A (0.51) ALDH1A1MEN1HPGDKMT2ARAB9A
SCHEMBL1812018 0.72 ALDH1A1 (0.45) ALDH1A1MEN1HPGDKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 — — EP disclosed
EP-3885340-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2021-09-29 — — EP disclosed
US-11046713-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2021-06-29 — — US disclosed
EP-3369732-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2021-05-26 — — EP disclosed
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2020-09-24 — — US disclosed
US-10711013-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2020-07-14 — — US disclosed
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2019-04-04 — — US disclosed
US-10118933-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2018-11-06 — — US disclosed
EP-3369732-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2018-09-05 — — EP disclosed
US-20170260206-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2017-09-14 — — US disclosed
US-9657003-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2017-05-23 — — US disclosed
EP-3056485-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS Orion Corporation (FI) 2016-08-17 — — EP disclosed
US-20150203479-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION 2015-07-23 — — US disclosed
US-8975254-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2015-03-10 — — US disclosed
EP-2493858-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2014-07-02 — — EP disclosed
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-09-06 — — US disclosed
EP-2493858-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS Orion Corporation (FI) 2012-09-05 — — EP disclosed
WO-2011051540-A9 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-06-21 — — WO disclosed
WO-2011051540-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2011-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260206-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-10118933-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-10711013-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-11046713-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-20150203479-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG PNMT 3291/4885ALDH1A1 570/4885MEN1 1934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.