Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549514 | 0.87 | GLRA1 (0.39) | GLRA1HTR2AHTR2CSLC6A4TSHR | |
| SCHEMBL17537079 | 0.80 | ALOX15 (0.36) | TSHR | |
| SCHEMBL28060091 | 0.79 | GLRA1 (0.49) | GLRA1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL28060108 | 0.79 | GLRA1 (0.49) | GLRA1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL17549494 | 0.78 | ALOX15 (0.35) | TSHR | |
| SCHEMBL17549497 | 0.78 | ALOX15 (0.35) | TSHR | |
| SCHEMBL17537080 | 0.78 | ALOX15 (0.35) | TSHR | |
| SCHEMBL17537202 | 0.77 | HTR1A (0.35) | TSHR | |
| SCHEMBL13849656 | 0.77 | GLRA1 (0.46) | GLRA1TSHRCETP | |
| SCHEMBL17537158 | 0.76 | ELANE (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | CYP2D6, CYP2B6, CYP2A6 | GLRA1 4066/4885HTR2A 2760/4885HTR2C 1665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.