SCHEMBL381475

SCHEMBL381475

CC1COC(c2ccc(C3=NC(C)CO3)cc2)=N1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 4/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12731994 0.92 MAPT (0.51) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL7913803 0.90 ENPP2 (0.43) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL7911822 0.90 ENPP2 (0.43) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL7386839 0.90 MAPT (0.47) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL6697450 0.86 KCNH2 (0.38) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL12731996 0.86 MEN1 (0.38) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL381302 0.84 NPC1 (0.62) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL14351707 0.84 NPC1 (0.62) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17552003 0.83 ADRA2A (0.42) MAPTNPC1
SCHEMBL2742839 0.83 ADRA2A (0.42) MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8545981-B2 Artificial hair made of flame-retardant polyester KANEKA CORPORATION (JP) 2013-10-01 US claimed
US-20130133676-A1 ARTIFICIAL HAIR MADE OF FLAME-RETARDANT POLYESTER KANEKA CORPORATION (JP) 2013-05-30 US claimed
US-8211542-B2 Artificial hair made of flame-retardant polyester KANEKA CORPORATION (JP) 2012-07-03 US claimed
US-20110269878-A1 Artificial Hair Made of Flame-Retardant Polyester KANEKA CORPORATION (JP) 2011-11-03 US claimed
US-20070184264-A1 Flame-retardant polyester artificial hair KANEKA CORPORATION (JP) 2007-08-09 US claimed
US-5091259-A Flame retardant, flexible POLYPLASTICS CO., LTD. (JP) 1992-02-25 US claimed
US-4987167-A Flexible dielectric coverings POLYPLASTICS CO., LTD. (JP) 1991-01-22 US claimed
EP-4725990-A1 RESIN COMPOSITION Sumitomo Chemical Company, Limited (JP) 2026-04-15 EP disclosed
EP-4674885-A1 POLYESTER, PRESSURE-SENSITIVE ADHESIVE AGENT COMPOSITION, PRESSURE-SENSITIVE ADHESIVE AGENT, PRESSURE-SENSITIVE ADHESIVE TAPE, AND PRESSURE-SENSITIVE ADHESIVE TAPE FOR ELECTRONIC MEMBERS Mitsubishi Chemical Corporation (JP) 2026-01-07 EP disclosed
US-20260001999-A1 HYDROPHILIC OIL REPELLENT POLYMER SUMITOMO CHEMICAL CO (JP) 2026-01-01 US disclosed
US-20250361356-A1 POLYESTER, ADHESIVE COMPOSITION, ADHESIVE, ADHESIVE TAPE, AND ADHESIVE TAPE FOR ELECTRONIC COMPONENTS MITSUBISHI CHEMICAL CORPORATION (JP) 2025-11-27 US disclosed
US-20250320357-A1 COMPOSITION SUMITOMO CHEMICAL CO (JP) 2025-10-16 US disclosed
EP-4206257-B1 SEMIAROMATIC POLYESTER, AND PREPARATION METHOD AND APPLICATION THEREOF JIANGSU KINGFA SCI & TECH ADV MAT CO LTD (CN) 2025-07-30 EP disclosed
EP-0382487-A2 Polyester resin composition POLYPLASTICS CO. LTD. (JP) 1990-08-16 EP disclosed
US-4931512-A REACTING POLY(CYCLIC IMINOETHER) WITH POLYOLS OR POLYAMINES, ACID CATALYST; CURABLE TEIJIN LIMITED (JP) 1990-06-05 US disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed
EP-0336390-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1989-10-11 EP disclosed
EP-0320159-A1 Flame-retardant resin composition and electric wire POLYPLASTICS CO. LTD. (JP) 1989-06-14 EP disclosed
EP-0314303-A2 Resin modifier and modified resin POLYPLASTICS CO. LTD. (JP) 1989-05-03 EP disclosed
EP-0273368-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001999-A1 HYDROPHILIC OIL REPELLENT POLYMER CCR1, H1-3, CCR3 MEN1 1349/4885KMT2A 1993/4885MAPT 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.