Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553668 | 0.91 | PTPN1 (0.43) | CASP3PTPN1MDM4TP53 | |
| SCHEMBL25329241 | 0.86 | CASP3 (0.50) | CASP3PTPN1MDM4TP53 | |
| SCHEMBL30972557 | 0.86 | CASP3 (0.50) | CASP3PTPN1MDM4TP53 | |
| SCHEMBL25329244 | 0.86 | CASP3 (0.50) | CASP3PTPN1MDM4TP53 | |
| SCHEMBL17553454 | 0.86 | PTPN1 (0.48) | PTPN1 | |
| SCHEMBL20415092 | 0.85 | CASP3 (0.49) | CASP3PTPN1MDM4TP53 | |
| SCHEMBL17553602 | 0.82 | CASP3 (0.47) | CASP3PTPN1MDM4TP53TNF | |
| SCHEMBL17553615 | 0.82 | ALDH1A1 (0.48) | — | |
| SCHEMBL12605223 | 0.81 | ALDH1A1 (0.55) | CASP3PTPN1 | |
| SCHEMBL118169 | 0.81 | MDM4 (0.59) | CASP3MDM4TP53TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |