Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553561 | 0.86 | CASP3 (0.48) | PTPN1 | |
| SCHEMBL17553670 | 0.85 | CTSL (0.47) | CTSLCPB2GHSRERAP2ERAP1 | |
| SCHEMBL17553455 | 0.84 | TLR2 (0.55) | PTPN1TLR2 | |
| SCHEMBL14374768 | 0.83 | PTPN1 (0.55) | PTPN1CTSLTLR2GRB2 | |
| SCHEMBL17553668 | 0.81 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL19423735 | 0.80 | TLR2 (0.59) | PTPN1TLR2 | |
| SCHEMBL19423749 | 0.79 | TLR2 (0.55) | PTPN1CTSLTLR2GRB2 | |
| SCHEMBL30193301 | 0.79 | TLR2 (0.53) | PTPN1CTSLTLR2 | |
| SCHEMBL30598967 | 0.79 | TLR2 (0.55) | PTPN1TLR2 | |
| SCHEMBL30150290 | 0.79 | TLR2 (0.53) | PTPN1CTSLTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |