Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | BACE1 | P56817 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957726 | 0.87 | L3MBTL1 (0.56) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL4893960 | 0.87 | L3MBTL1 (0.56) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL13754804 | 0.87 | L3MBTL1 (0.56) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL2680934 | 0.87 | L3MBTL1 (0.56) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL1705362 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL1705363 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL12995094 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL6397984 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL1755571 | 0.79 | L3MBTL1 (0.49) | L3MBTL1ACHEBACE1LMNAKMT2A | |
| SCHEMBL8415735 | 0.75 | KMT2A (0.63) | L3MBTL1ACHEBACE1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203562-B1 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY AND/OR DIASTEREOMERICALLY ENRICHED ESTER, THIOESTER, ALCOHOL OR THIOL | DSM IP ASSETS BV (NL) | 2012-04-18 | — | — | EP | disclosed |