SCHEMBL4893960

SCHEMBL4893960

C(=NC1CCCCC1N=Cc1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
LMNA P02545 1/20 0.46
ACHE P22303 7/20 0.45
BACE1 P56817 7/20 0.45
KMT2A Q03164 1/20 0.44
BCHE P06276 3/20 0.42
THRB P10828 2/20 0.42
GAA P10253 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
NOX1 Q9Y5S8 1/20 0.38
GRIN1 Q05586 2/20 0.36
GRIN2B Q13224 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13754804 1.00 L3MBTL1 (0.56) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL13957726 1.00 L3MBTL1 (0.56) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL2680934 1.00 L3MBTL1 (0.56) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL1705363 0.87 L3MBTL1 (0.49) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL12995094 0.87 L3MBTL1 (0.49) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL1705362 0.87 L3MBTL1 (0.49) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL1755570 0.87 L3MBTL1 (0.45) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL1755571 0.87 L3MBTL1 (0.49) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL6397984 0.87 L3MBTL1 (0.49) L3MBTL1LMNAACHEBACE1KMT2A
SCHEMBL8415735 0.83 KMT2A (0.63) L3MBTL1LMNAACHEBACE1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663633-B2 Composition based on natural rubber and on a polyaldimine compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-05-30 US claimed
WO-2013117458-A1 COMPOSITION BASED ON NATURAL RUBBER AND ON A POLYALDIMINE COMPOUND COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2013-08-15 WO claimed
EP-4722190-A1 SUSTAINABLE SYNTHESIS OF A TERPENYLAMINE IN THE PRESENCE OF AT LEAST ONE ZINC-BASED PRECURSOR Nantes Université (FR) 2026-04-08 EP disclosed
US-9714339-B2 Rubber composition comprising an epoxy resin and a polyimine hardener COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-07-25 US disclosed
US-9663633-B2 Composition based on natural rubber and on a polyaldimine compound COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-05-30 US disclosed
US-20150183983-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER MICHELIN RECHERCHE ET TECHNIQUE, S.A. (CH) 2015-07-02 US disclosed
EP-2877526-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER Compagnie Générale des Etablissements Michelin (FR) 2015-06-03 EP disclosed
US-8853352-B2 Functionalized polymer and method for making BRIDGESTONE CORPORATION (JP) 2014-10-07 US disclosed
WO-2014016346-A1 RUBBER COMPOSITION COMPRISING AN EPOXY RESIN AND A POLYIMINE HARDENER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-30 WO disclosed
WO-2014016344-A1 RUBBER COMPOSITION COMPRISING A LIGNIN-BASED RESIN COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-30 WO disclosed
WO-2013117458-A1 COMPOSITION BASED ON NATURAL RUBBER AND ON A POLYALDIMINE COMPOUND COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2013-08-15 WO disclosed
US-20080154020-A1 introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica BRIDGESTONE CORPORATION (JP) 2008-06-26 US disclosed
US-4120957-A ANTHELMINTICS ROHM AND HAAS COMPANY (US) 1978-10-17 US disclosed