Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705363 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL6397984 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL12995094 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL1755571 | 1.00 | L3MBTL1 (0.49) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL13754804 | 0.87 | L3MBTL1 (0.56) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL2680934 | 0.87 | L3MBTL1 (0.56) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL4893960 | 0.87 | L3MBTL1 (0.56) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL13957726 | 0.87 | L3MBTL1 (0.56) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL1755570 | 0.79 | L3MBTL1 (0.45) | L3MBTL1KMT2ATHRBACHEBACE1 | |
| SCHEMBL11836200 | 0.78 | L3MBTL1 (0.41) | L3MBTL1KMT2ATHRBACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203562-B1 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY AND/OR DIASTEREOMERICALLY ENRICHED ESTER, THIOESTER, ALCOHOL OR THIOL | DSM IP ASSETS BV (NL) | 2012-04-18 | — | — | EP | disclosed |
| US-20100304451-A1 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY AND/OR DIASTEREOMERICALLY ENRICHED ESTER, THIOESTER, ALCOHOL OR THIOL | DSM IP ASSETS B.V. (NL) | 2010-12-02 | — | — | US | disclosed |
| US-6939986-B2 | Process for preparing 1,2-diamino compounds | HOFFMANN-LA ROCHE INC. (US) | 2005-09-06 | — | — | US | disclosed |
| EP-1059283-B1 | Process for preparing neuraminidase inhibitor ro-64-0796 | HOFFMANN LA ROCHE (CH) | 2003-05-28 | — | — | EP | disclosed |
| US-6437171-B1 | AZIDE-FREE; PREPARING 2-AMINOALCOHOLS FROM 1,2-EPOXIDES AND AN AMINE; PROTECTING THE FREE AMINO GROUP, HYDROXY LEAVING GROUP, DEPROTECTING, REACTING WITH AN AMINE, ACYLATING, DEPROTECTING | HOFFMAN-LA ROCHE INC. | 2002-08-20 | — | — | US | disclosed |
| US-20020095040-A1 | Process for preparing 1,2-diamino compounds | KARPF MARTIN (CH) | 2002-07-18 | — | — | US | disclosed |
| EP-1059283-A1 | Process for preparing neuraminidase inhibitor ro-64-0796 | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095040-A1 | Process for preparing 1,2-diamino compounds | AOC1, UGT1A1, THPO | L3MBTL1 4837/4885KMT2A 1119/4885THRB 4819/4885 |
| US-20100304451-A1 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY AND/OR DIASTEREOMERICALLY ENRICHED ESTER, THIOESTER, ALCOHOL OR THIOL | ADH1C, ACOT7, ADH5 | L3MBTL1 1357/4885KMT2A 976/4885THRB 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.