SCHEMBL17558191

SCHEMBL17558191

CC(O)(COC(=O)c1ccc(O)cc1)Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
MAPK1 P28482 3/20 0.50
ESR1 P03372 4/20 0.49
ESR2 Q92731 3/20 0.49
HIF1A Q16665 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
TSHR P16473 3/20 0.47
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 3/20 0.46
SLC6A2 P23975 2/20 0.46
CHRM1 P11229 1/20 0.46
KDR P35968 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 1/20 0.45
CYP2D6 P10635 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150408 0.77 MAPK1 (0.56) LMNAMAPK1ESR1ESR2HIF1A
SCHEMBL1728720 0.76 MAPK1 (0.64) LMNAMAPK1ESR1ESR2HIF1A
SCHEMBL27559017 0.76 MAPK1 (0.69) LMNAMAPK1HIF1ATSHRTDP1
SCHEMBL18652233 0.76 MAPK1 (0.64) LMNAMAPK1ESR1ESR2HIF1A
SCHEMBL23484566 0.76 MAPK1 (0.64) LMNAMAPK1ESR1ESR2HIF1A
SCHEMBL21540536 0.75 MAPK1 (0.62) LMNAMAPK1HIF1ATSHRTDP1
SCHEMBL7114343 0.74 LMNA (0.45) LMNAMAPK1ESR1ESR2CA12
SCHEMBL5990376 0.74 ELANE (0.41) MAPK1HIF1ATSHRTDP1ALDH1A1
SCHEMBL2042074 0.74 THRB (0.53) MAPK1HIF1ATSHRALDH1A1KMT2A
SCHEMBL9564941 0.73 ESR1 (0.65) LMNAMAPK1ESR1ESR2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2994201-B1 COMPOSITIONS WITH HIGH QUANTITIES OF UV STABILIZERS BASF SE (DE) 2017-12-20 EP disclosed
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS ERCC5, ERCC1, TTPA LMNA 1326/4885MAPK1 4008/4885ESR1 2890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.