Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 8/20 | 0.42 |
| ▸ | PLAT | P00750 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.39 |
| ▸ | F7 | P08709 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5476512 | 0.84 | BCAT2 (0.59) | BCAT2PLAUPLATLTB4RLTB4R2 | |
| SCHEMBL29137601 | 0.79 | ALDH1A1 (0.45) | LTB4RLTB4R2PDCD1CD274SMN1; SMN2 | |
| SCHEMBL15839774 | 0.76 | PPARG (0.44) | LTB4R2 | |
| SCHEMBL1034554 | 0.75 | BCAT2 (0.63) | BCAT2PLAUPLATPRSS1PRSS2 | |
| SCHEMBL32689453 | 0.75 | BCAT2 (0.63) | BCAT2PLAUPLATPRSS1PRSS2 | |
| SCHEMBL528810 | 0.75 | BCL2L1 (0.52) | LTB4RLTB4R2PDCD1CD274SMN1; SMN2 | |
| SCHEMBL1406272 | 0.75 | ALDH1A1 (0.52) | PDCD1CD274SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL29131061 | 0.74 | BCAT2 (0.61) | BCAT2PLAUPLATPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL31621742 | 0.74 | BCAT2 (0.61) | BCAT2PLAUPLATPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL27450056 | 0.74 | BCAT2 (0.61) | BCAT2PLAUPLATPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189026-A1 | ESTROGEN RECEPTOR LIGAND TREATMENT FOR NEURODEGENERATIVE DISEASES | The Regents of The University of California (US) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016036721-A1 | ESTROGEN RECEPTOR LIGAND TREATMENT FOR NEURODEGENERATIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-10 | — | — | WO | disclosed |